Endocrine Abstracts

Benzophenones are organic chemicals widely used as stabilizers to UV light irradiation in plastic surface coatings and food packaging. They have been known that their derivatives appear to have cytotoxic effects. 2-Hydroxy-4-methoxybenzophenone (Benzophenone-3, BP-3) and its metabolite, 2,4-dihydroxybenzophenone (Benzophenone-1, BP-1), are used mostly in the formulation of nail polishes, enamels, bath products, sunscreens and skin care products. In this study, the estrogenic e...

IntroductionAntithyroid drugs are widely used in the therapy of hyperthyroidism. This review (update of Cochrane review: Antithyroid drug regimen for treating Graves' hyperthyroidism. In: The Cochrane Library, Issue 4, 2003; with 4 additional trials) assesses the effects of dose, regimen and duration of antithyroid drug therapy for Graves' hyperthyroidism.MethodsThe Cochrane Controlled Trials Register, MEDLIN...

While iodine deficiency goitre is common worldwide, it is rarely described in the U.K. Vegan diet is the only real way for this deficiency to occur in the U.K. A MEDLINE search from 1966 revealed 1 reported case (Shaikh et al. Transient neonatal hypothyroidism due to a maternal vegan diet; Journal of Pediatric Endocrinology & Metabolism Jan 2003). We have identified 3 cases, which we will describe here.Case 1A 21-year-ol...

Purpose: Although some studies presented good outcome of Radiofrequency Ablation (RFA) for Papillary Thyroid microcarcinoma (PTMC), its benefit has not been fully elucidated. The purpose of our study was to report the results from a prospective study investigating efficacy and safety of RFA in active surveillance candidate for low-risk PTMC. Materials and Methods: Since November 2018, RFA has been prospectively performed in active surveillance candidates...

Objective: In this study, we investigated the utility of Doppler and microvascular imaging in diagnosing benign and malignant thyroid nodules according to the TI-RADS (Thyroid Imaging Reporting and Data System) and pathologic subtypes of thyroid malignancy.Methods: Total 113 pathologically confirmed thyroid nodules (n =72 (63.7%) benign, n =41 (36.3%) malignant) from103 patients who visited for evaluation of thyroid nodules in single te...

Background: It has been studied that larger tumor size in T3b has a worse prognosis than T3b with smaller tumor size. The present study aims to compare the clinicopathological characteristics among modified T categories and clarify the significance of tumor size in T3b on the DSS of differentiated thyroid carcinoma(DTC).Methods: A total of 6282 patients with DTC who underwent thyroid surgery at a single center were retrospectively analyzed. Patients with...

Background: To evaluate the technical feasibility, effectiveness, and safety of transoral robotic thyroidectomy (TORT), using the da Vinci system through analysis of our series of 1000 consecutive patients.Method: A review of a prospectively designed database at our institute from September 2012 to February 2022 revealed a series of 1000 consecutive TORT patients with preoperative diagnosis of various thyroid diseases. Clinicopathologic characteristics a...

Purpose: We conducted this study to determine the prevalence and incidence of pituitary tumors in South Korea.Methods: This is a nationwide population- based retrospective study. We analysed two national databases, the Korean National Health Insurance (NHI) claims database and Rare Intractable Disease (RID) registration database, which include information on every patients with pituitary tumor diagnosed through uniform criteria from 2009 to 2013. Pituita...

Objectives: Prolactin (PRL) normalization after 3 months of Cabergoline (CAB) treatment are useful predictors of responsiveness in patients with prolactinoma. However, differences within the PRL normalization cut-off value have not been identified.Methods: We reviewed the medical records of patients with prolactinomas who were treated with CAB as a primary drug at Severance Hospital. We included patients who had a full dataset of pituitary hormone assays...

Objective: Apolipoprotein B/Apolipoprotein A-1 ratio (Apo B/Apo A-1) and lipoprotein (a) (Lp(a)) are known to be associated with atherosclerotic vascular disease. We investigated the influence of Apo B/Apo A-1 and Lp(a) on coronary artery calcification (CAC) among healthy Korean adults.Methods: A total of 1081 participants underwent cardiac computed tomography in health promotion center were enrolled. Anthropometric profiles and multiple cardiovascular r...